Clinical Trials as Topic

Determination of Clinically Relevant Cutoffs for HIV-1 Phenotypic Resistance Estimates Through a Combined Analysis of Clinical Trial and Cohort Data

BACKGROUND:: Clinically relevant cutoffs are needed for the interpretation of HIV-1 phenotypic resistance estimates as predicted by ''virtual'' phenotype HIV resistance analysis. METHODS:: Using a clinical data set containing 2596 treatment change …

Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: response

Use of composite end points to measure clinical events

Use of composite end points to measure clinical events